Low Birthweight in Second Children After Nurse Home Visiting




Margaret L. Holland, Susan W. Groth, Joyce A. Smith, Ying Meng, and Harriet Kitzman,

Brief Type

Journal Publication


  • Nurse-Family Partnership (NFP)


Objective: To examine low birthweight and preterm birth of second children born to home-visited first-time mothers. Subjects: Women were previously recruited for a randomized controlled trial of the home visiting model disseminated as Nurse-Family Partnership. 512 of these women had second children within 18 years of the first child’s birth, and were included in our sample. Results: The intervention was associated with a lower likelihood of low birthweight for second children (odds ratio: 0.51, 95% CI: 0.27, 0.97), an effect apparent only if the first born had low birthweight and mediated by close birth spacing. These moderation and mediation patterns were similar in the preterm birth outcome. Conclusion: A home visiting program provided for first-born children reduced low birthweight for second-born children, if the first-born had low birthweight. This finding implies a broader impact than previously documented, because few studies have included these second children. (author abstract)

Data Collection Methods

  • Program administrative record reviews



For More Information

Holland, M. L., Groth, S. W., Smith, J. A., Meng, Y., & Kitzman, H. (2018). Low birthweight in second children after nurse home visiting. Journal of Perinatology38(12), 1610-1619. doi:10.1038/s41372-018-0222-8 
Author Contact Information:
Margaret L. Holland


  • Participant, Family, and Program Outcomes